PI: Dennis Selkoe
Affiliation: Harvard Medical School and Brigham & Women's Hospital
Submitted by: Dennis Selkoe
Posted Date: 23 Feb 2009

Brief Description

This is a protocol for measuring the enzymatic activity of neprilysin, an Aβ-degrading enzyme.

References

1. Hemming ML, Patterson M, Reske-Nielsen C, Lin L, Isacson O, Selkoe DJ. Reducing amyloid plaque burden via ex vivo gene delivery of an Abeta-degrading protease: a novel therapeutic approach to Alzheimer disease. PLoS Med. 2007 Aug;4(8):e262. PubMed.

Keywords

Aβ degrading enzyme, degradation

Further Reading

No Available Further Reading