This is a protocol for measuring the enzymatic activity of neprilysin, an Aβ-degrading enzyme.
- Hemming ML, Patterson M, Reske-Nielsen C, Lin L, Isacson O, Selkoe DJ. Reducing amyloid plaque burden via ex vivo gene delivery of an Abeta-degrading protease: a novel therapeutic approach to Alzheimer disease. PLoS Med. 2007 Aug;4(8):e262. PubMed.
Aβ degrading enzyme, degradation