. Visinin-like protein-1: diagnostic and prognostic biomarker in Alzheimer disease. Ann Neurol. 2011 Aug;70(2):274-85. PubMed.

AlzBiomarker Database

Meta-Analysis

Curated Study Data

Biomarker
(Source)
Cohort
(N)
Measurement
Mean ± SD
Method;
Assay Name;
Manufacturer
Diagnostic
Criteria
Aβ1-42
(CSF)
AD
(98)
390 ± 175
pg/mL
ELISA;
Innotest;
Innogenetics
Morris et al., 2006; Berg et al., 1998
Aβ1-42
(CSF)
CTRL-
CNC
(211)
615 ± 246
pg/mL
ELISA;
Innotest;
Innogenetics
VLP-1
(CSF)
AD
(98)
520 ± 171
pg/mL
Single Molecule Counting Immunoassay;
Erenna;
Singulex, Inc.
Morris et al., 2006; Berg et al., 1998
VLP-1
(CSF)
CTRL-
CNC
(211)
396 ± 149
pg/mL
Single Molecule Counting Immunoassay;
Erenna;
Singulex, Inc.
tau-p181
(CSF)
AD
(98)
90 ± 42
pg/mL
ELISA;
Innotest;
Innogenetics
Morris et al., 2006; Berg et al., 1998
tau-p181
(CSF)
CTRL-
CNC
(211)
54 ± 23
pg/mL
ELISA;
Innotest;
Innogenetics
tau-total
(CSF)
AD
(98)
602 ± 282
pg/mL
ELISA;
Innotest;
Innogenetics
Morris et al., 2006; Berg et al., 1998
tau-total
(CSF)
CTRL-
CNC
(211)
295 ± 159
pg/mL
ELISA;
Innotest;
Innogenetics

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