Rockwood K, Kirkland S, Hogan DB, Macknight C, Merry H, Verreault R, Wolfson C, McDowell I.
Use of lipid-lowering agents, indication bias, and the risk of dementia in community-dwelling elderly people.
Arch Neurol. 2002 Feb;59(2):223-7.
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Together these papers (Locatelli et al., Okamura et al., and Rockwood et al.) further the interesting link between cholesterol metabolism and AD
This paper provides further support for the observation that use of statins is associated with a lower risk of AD. Specifically, this paper reduces the possibility that the negative correlation between statin use and AD is due to the a spurious outcome of doctor prescribing characteristics, rather than a real action of statins on some aspect of the pathophysiology of AD.