Raices M, Maruyama H, Dillin A, Karlseder J.
Uncoupling of longevity and telomere length in C. elegans.
PLoS Genet. 2005 Sep;1(3):e30.
Please login to recommend the paper.
Make a Comment
This paper raises several provocative issues. It also lends further support to those who believe that the secondary function of telomeres is to serve as a checkpoint for uncontrolled cellular proliferation. This makes sense in tissues that continue to undergo mitosis. But it raises the question, "What is the function of telomeres in non-replicative cells?" They must have some function; what is their function and why are they there? I have an idea but would like to hear from others first.
To make a comment you must login or register.