Schwab C, Hosokawa M, McGeer PL.
Transgenic mice overexpressing amyloid beta protein are an incomplete model of Alzheimer disease.
Exp Neurol. 2004 Jul;188(1):52-64.
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The title of this paper should, apparently really be "Transgenic mice overexpressing amyloid beta protein ALONE are an incomplete ----". When expression of mutated APP is combined with expression of other mutated proteins important in AD pathology these t.g. mice exhibit a rich array of AD characteristics (e.g. LaFerla, 2003).
Oddo S, Caccamo A, Kitazawa M, Tseng BP, Laferla FM.
Amyloid deposition precedes tangle formation in a triple transgenic model of Alzheimer's disease.
Neurobiol Aging. 2003 Dec;24(8):1063-70.
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