. Tau protein in cerebrospinal fluid is significantly increased at the earliest clinical stage of Alzheimer disease. Alzheimer Dis Assoc Disord. 1998 Dec;12(4):372-7. PubMed.

AlzBiomarker Database

Meta-Analysis

Curated Study Data

Biomarker
(Source)
Cohort
(N)
Measurement
Mean ± SD
Method;
Assay Name;
Manufacturer
Diagnostic
Criteria
tau-total
(CSF)
AD-
Mild-to-Moderate AD
(21)
743.2 ± 465.5
pg/mL
ELISA;
Innotest;
Innogenetics
McKhann et al., 1984
tau-total
(CSF)
AD-
Very Mild AD
(19)
646.36 ± 425.06
pg/mL
ELISA;
Innotest;
Innogenetics
McKhann et al., 1984
tau-total
(CSF)
CTRL-
CNC
(36)
168.8 ± 63.8
pg/mL
ELISA;
Innotest;
Innogenetics

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AlzBiomarker

  1. AD vs CTRL : tau-total (CSF)