. Structure, microtubule interactions, and paired helical filament aggregation by tau mutants of frontotemporal dementias. Biochemistry. 2000 Sep 26;39(38):11714-21. PubMed.

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Mutations

  1. MAPT K280del
  2. MAPT P301L

Research Models

  1. TauRDΔK280 (“Proaggregation mutant”)