. Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease. Ann Neurol. 1999 Dec;46(6):860-6. PubMed.

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  1. This report shifts the importance of Abeta in AD from the amyloid depositions to a soluble Abeta peptide. This shift is nessasary as there is good evidence that amyloid plaques may not be responsible for AD.