. Proteomic and functional analyses reveal a mitochondrial dysfunction in P301L tau transgenic mice. J Biol Chem. 2005 Jun 24;280(25):23802-14. PubMed.


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  1. The study extends insights into the consequences of tau pathology that involve a mitochondrial and oxidative stress.

  2. An interesting paper, suggesting involvement of mitochondria in fronto-temporal dementia.

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