Skoog I, Wallin A, Fredman P, Hesse C, Aevarsson O, Karlsson I, Gottfries CG, Blennow K. A population study on blood-brain barrier function in 85-year-olds: relation to Alzheimer's disease and vascular dementia. Neurology. 1998 Apr;50(4):966-71. PubMed.
AlzBiomarker Database
Meta-Analysis
Curated Study Data
| Biomarker (Source) |
Cohort (N) |
Measurement Mean ± SD |
Method; Assay Name; Manufacturer |
Diagnostic Criteria |
|---|---|---|---|---|
| albumin ratio (CSF/Blood) |
AD (13) |
8.9 ± 5.3 (CSF mg/L)/(Serum g/L) |
Immunoelectrophoresis; Other/Not Specified; In-house |
McKhann et al., 1984 |
| albumin ratio (CSF/Blood) |
CTRL- CNC (29) |
6.5 ± 2 (CSF mg/L)/(Serum g/L) |
Immunoelectrophoresis; Other/Not Specified; In-house |
|
| albumin ratio (CSF/Blood) |
VaD (14) |
8.7 ± 3.5 (CSF mg/L)/(Serum g/L) |
Immunoelectrophoresis; Other/Not Specified; In-house |
Román et al., 1993 |
Recommends
Please login to recommend the paper.
Comments
Banner Research Institute
The evidence supporting a BBB dysfunction in elderly demented patents in this paper adds further weight to a (uncertain) role of the BBB in AD and other pathologies.
Make a Comment
To make a comment you must login or register.