. Plasma phospho-tau181 increases with Alzheimer's disease clinical severity and is associated with tau- and amyloid-positron emission tomography. Alzheimers Dement. 2018 Aug;14(8):989-997. Epub 2018 Apr 5 PubMed.

AlzBiomarker Database

Meta-Analysis

Curated Study Data

Biomarker
(Source)
Cohort
(N)
Measurement
Mean ± SD
Method;
Assay Name;
Manufacturer
Diagnostic
Criteria
tau-p181
(Plasma)
AD
(40)
11.6 ± 4.1
pg/mL
Electrochemiluminescence;
Other/Not Specified;
Meso Scale Discovery
McKhann et al., 2011
tau-p181
(Plasma)
CTRL-
CNC
(172)
6.4 ± 6.4
pg/mL
Electrochemiluminescence;
Other/Not Specified;
Meso Scale Discovery
tau-total
(Plasma)
AD
(40)
7.2 ± 2.8
pg/mL
SIMOA;
hTau kit (101444);
Quanterix
McKhann et al., 2011
tau-total
(Plasma)
CTRL-
CNC
(172)
5.9 ± 1.9
pg/mL
SIMOA;
hTau kit (101444);
Quanterix

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