Lue LF, Sabbagh MN, Chiu MJ, Jing N, Snyder NL, Schmitz C, Guerra A, Belden CM, Chen TF, Yang CC, Yang SY, Walker DG, Chen K, Reiman EM. Plasma Levels of Aβ42 and Tau Identified Probable Alzheimer's Dementia: Findings in Two Cohorts. Front Aging Neurosci. 2017;9:226. Epub 2017 Jul 24 PubMed.
AlzBiomarker Database
Meta-Analysis
- AD vs CTRL : Aβ42 (Plasma and Serum)
- CTRL vs AD : Aβ42 (Plasma and Serum)
- AD vs CTRL : tau-total (Plasma and Serum)
- CTRL vs AD : tau-total (Plasma and Serum)
Curated Study Data
| Biomarker (Source) |
Cohort (N) |
Measurement Mean ± SD |
Method; Assay Name; Manufacturer |
Diagnostic Criteria |
|---|---|---|---|---|
| Aβ42 (Plasma) |
AD (16) |
16.8 ± 0.37† pg/mL |
Immunomagnetic Reduction; MF-AB2-0060; MagQu Co. Ltd. |
|
| Aβ42 (Plasma) |
CTRL- CNC (16) |
15.33 ± 0.66† pg/mL |
Immunomagnetic Reduction; MF-AB2-0060; MagQu Co. Ltd. |
|
| tau-total (Plasma) |
AD (16) |
34.52 ± 3.75† pg/mL |
Immunomagnetic Reduction; MF-TAU-0060; MagQu Co. Ltd. |
|
| tau-total (Plasma) |
CTRL- CNC (16) |
20.48 ± 1.24† pg/mL |
Immunomagnetic Reduction; MF-TAU-0060; MagQu Co. Ltd. |
† Mean ± SEM
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