Devanand DP, Mikhno A, Pelton GH, Cuasay K, Pradhaban G, Dileep Kumar JS, Upton N, Lai R, Gunn RN, Libri V, Liu X, Van Heertum R, Mann JJ, Parsey RV. Pittsburgh compound B (11C-PIB) and fluorodeoxyglucose (18 F-FDG) PET in patients with Alzheimer disease, mild cognitive impairment, and healthy controls. J Geriatr Psychiatry Neurol. 2010 Sep;23(3):185-98. PubMed.
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Banner Research Institute
It would be interesting to determine correlations between PIB binding and FDG within each region studied. Assuming that FDG provides a global approximation of synaptic activity, such correlations may provide an indication of the relationship between PIB binding and synaptic activity.
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