. Pittsburgh compound B (11C-PIB) and fluorodeoxyglucose (18 F-FDG) PET in patients with Alzheimer disease, mild cognitive impairment, and healthy controls. J Geriatr Psychiatry Neurol. 2010 Sep;23(3):185-98. PubMed.


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  1. It would be interesting to determine correlations between PIB binding and FDG within each region studied. Assuming that FDG provides a global approximation of synaptic activity, such correlations may provide an indication of the relationship between PIB binding and synaptic activity.