. Phosphatidylinositol and inositol involvement in Alzheimer amyloid-beta fibril growth and arrest. J Mol Biol. 1998 Apr 24;278(1):183-94. PubMed.


Please login to recommend the paper.


  1. This is a nice paper because it examines the role of lipids in amyloid formation. Such a role was already indicated by several laboratories. There are good evidence indications that the first seeds of amyloid fibrils may form on membranes.

  2. At neutral pH, PI influences amyloidosis of in vitro Ab1-42 but not Ab1-40. This may be relevant with the presence of diffuse plaque formation.

Make a Comment

To make a comment you must login or register.

This paper appears in the following:


  1. Aβ Busters and Other Ploys Show Promise for Treating Neurodegeneration