. Patients with amyotrophic lateral sclerosis and other neurodegenerative diseases have increased levels of neurofilament protein in CSF. J Neurochem. 1996 Nov;67(5):2013-8. PubMed.

AlzBiomarker Database

Meta-Analysis

Curated Study Data

Biomarker
(Source)
Cohort
(N)
Measurement
Mean ± SD
Method;
Assay Name;
Manufacturer
Diagnostic
Criteria
NFL
(CSF)
AD
(11)
346 ± 176
pg/mL
ELISA;
Other/Not Specified;
In-house
McKhann et al., 1984
NFL
(CSF)
ALS
(12)
1743 ± 1661
pg/mL
ELISA;
Other/Not Specified;
In-house
Brooks, 1994
NFL
(CSF)
CTRL-
CNC
(34)
138 ± 31
pg/mL
ELISA;
Other/Not Specified;
In-house

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