. New Alzheimer's disease locus on chromosome 8. J Med Genet. 2006 Dec;43(12):931-5. PubMed.


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  1. An interesting paper assessing a dozen Swedish families with AD in an attempt to identify a new locus. The authors present data that support (but do not prove) a new locus for AD on chr 8. This is based on a segregating haplotype across the centromere of chr 8 in two distinct families. As the authors note, more affected members or families and the identification of a single ancestral haplotype would strengthen this argument.

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