. Measurement of thirteen biological markers in CSF of patients with Alzheimer's disease and other dementias. Dement Geriatr Cogn Disord. 2006;21(1):9-15. Epub 2005 Oct 21 PubMed.

AlzBiomarker Database

Meta-Analysis

Curated Study Data

Biomarker
(Source)
Cohort
(N)
Measurement
Mean ± SD
Method;
Assay Name;
Manufacturer
Diagnostic
Criteria
Aβ1-42
(CSF)
AD
(23)
410.6 ± 60†
pg/mL
ELISA;
Innotest;
Innogenetics
McKhann et al., 1984
Aβ1-42
(CSF)
CTRL-
CNC
(27)
866.8 ± 73†
pg/mL
ELISA;
Innotest;
Innogenetics
MCP-1
(CSF)
AD
(23)
733 ± 44†
pg/mL
ELISA;
Other/Not Specified;
R&D Systems, Inc.
McKhann et al., 1984
MCP-1
(CSF)
CTRL-
CNC
(27)
658 ± 85†
pg/mL
ELISA;
Other/Not Specified;
R&D Systems, Inc.
tau-p181
(CSF)
AD
(23)
58.9 ± 8†
pg/mL
ELISA;
Innotest;
Innogenetics
McKhann et al., 1984
tau-p181
(CSF)
CTRL-
CNC
(27)
22.8 ± 2†
pg/mL
ELISA;
Innotest;
Innogenetics
tau-total
(CSF)
AD
(23)
716.6 ± 101†
pg/mL
ELISA;
Innotest;
Innogenetics
McKhann et al., 1984
tau-total
(CSF)
CTRL-
CNC
(27)
297.1 ± 54†
pg/mL
ELISA;
Innotest;
Innogenetics

† Mean ± SEM

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