Olsson A, Höglund K, Sjögren M, Andreasen N, Minthon L, Lannfelt L, Buerger K, Möller HJ, Hampel H, Davidsson P, Blennow K. Measurement of alpha- and beta-secretase cleaved amyloid precursor protein in cerebrospinal fluid from Alzheimer patients. Exp Neurol. 2003 Sep;183(1):74-80. PubMed.

AlzBiomarker Database

Meta-Analysis

Curated Study Data

Biomarker
(Source)		 Cohort
(N)		 Measurement
Mean ± SD		 Method;
Assay Name;
Manufacturer		 Diagnostic
Criteria
Aβ42
(CSF)		 AD
(36)		 372 ± 163
pg/mL §		 ELISA;
Innotest;
Innogenetics		 McKhann et al., 1984
Aβ42
(CSF)		 AD
(45)		 534 ± 203
pg/mL §		 ELISA;
Innotest;
Innogenetics		 McKhann et al., 1984
Aβ42
(CSF)		 CTRL-
CNC
(12)		 839 ± 326
pg/mL §		 ELISA;
Innotest;
Innogenetics
Aβ42
(CSF)		 CTRL-
CNC
(30)		 858 ± 213
pg/mL §		 ELISA;
Innotest;
Innogenetics
sAPPα
(CSF)		 AD
(36)		 1968 ± 706
µg/L §		 ELISA;
Other/Not Specified;
In-house		 McKhann et al., 1984
sAPPα
(CSF)		 AD
(45)		 1710 ± 598
µg/L §		 ELISA;
Other/Not Specified;
In-house		 McKhann et al., 1984
sAPPα
(CSF)		 CTRL-
CNC
(12)		 2141 ± 595
µg/L §		 ELISA;
Other/Not Specified;
In-house
sAPPα
(CSF)		 CTRL-
CNC
(30)		 1644 ± 456
µg/L §		 ELISA;
Other/Not Specified;
In-house
sAPPβ
(CSF)		 AD
(36)		 1376 ± 159
µg/L §		 ELISA;
Other/Not Specified;
In-house		 McKhann et al., 1984
sAPPβ
(CSF)		 AD
(45)		 1806 ± 336
µg/L §		 ELISA;
Other/Not Specified;
In-house		 McKhann et al., 1984
sAPPβ
(CSF)		 CTRL-
CNC
(12)		 1280 ± 131
µg/L §		 ELISA;
Other/Not Specified;
In-house
sAPPβ
(CSF)		 CTRL-
CNC
(30)		 1792 ± 385
µg/L §		 ELISA;
Other/Not Specified;
In-house

§ Data supplied to Alzforum by author

Recommends

Please login to recommend the paper.

Comments

No Available Comments

Make a Comment

To make a comment you must login or register.