Toft M, Sando SB, Melquist S, Ross OA, White LR, Aasly JO, Farrer MJ.
LRRK2 mutations are not common in Alzheimer's disease.
Mech Ageing Dev. 2005 Nov;126(11):1201-5.
PubMed.
This is the first paper to assess the potential overlap between PD and AD with respect to mutations in LRRK2. To more definitively exclude a role of LRRK2 in AD, more samples need to be screened, in particular those showing a familial aggregation of AD and linkage to chromosome 12q12.
Comments
University of Lübeck
This is the first paper to assess the potential overlap between PD and AD with respect to mutations in LRRK2. To more definitively exclude a role of LRRK2 in AD, more samples need to be screened, in particular those showing a familial aggregation of AD and linkage to chromosome 12q12.
Make a Comment
To make a comment you must login or register.