Picconi B, Centonze D, Håkansson K, Bernardi G, Greengard P, Fisone G, Cenci MA, Calabresi P.
Loss of bidirectional striatal synaptic plasticity in L-DOPA-induced dyskinesia.
Nat Neurosci. 2003 May;6(5):501-6.
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These papers provide support for Parkinson's disease therapies and a basis for understanding L-DOPA's iatrogenic effects. It is curious that the GDNF recovery of function proceeded even as brain deterioration progressed.