Landgren S, Palmér MS, Skoog I, Minthon L, Wallin A, Andreasen N, Zetterberg M, Blennow K, Zetterberg H. No association of VEGF polymorphims with Alzheimer's disease. Neuromolecular Med. 2010 Sep;12(3):224-8. Epub 2009 Oct 20 PubMed.
AlzBiomarker Database
Meta-Analysis
- AD vs CTRL : Aβ42 (CSF)
- CTRL vs AD : Aβ42 (CSF)
- AD vs CTRL : tau-p181 (CSF)
- CTRL vs AD : tau-p181 (CSF)
- AD vs CTRL : tau-total (CSF)
- CTRL vs AD : tau-total (CSF)
Curated Study Data
| Biomarker (Source) |
Cohort (N) |
Measurement Mean ± SD |
Method; Assay Name; Manufacturer |
Diagnostic Criteria |
|---|---|---|---|---|
| Aβ42 (CSF) |
AD (801) |
456.7 ± 159 pg/mL |
ELISA; Innotest; Innogenetics |
McKhann et al., 1984 |
| Aβ42 (CSF) |
CTRL- CNC (286) |
712 ± 188.3 pg/mL |
ELISA; Innotest; Innogenetics |
|
| tau-p181 (CSF) |
AD (801) |
81.4 ± 33.3 pg/mL |
ELISA; Innotest; Innogenetics |
McKhann et al., 1984 |
| tau-p181 (CSF) |
CTRL- CNC (286) |
62.1 ± 18.1 pg/mL |
ELISA; Innotest; Innogenetics |
|
| tau-total (CSF) |
AD (801) |
667.8 ± 313.3 pg/mL |
ELISA; Innotest; Innogenetics |
McKhann et al., 1984 |
| tau-total (CSF) |
CTRL- CNC (286) |
350.7 ± 155.2 pg/mL |
ELISA; Innotest; Innogenetics |
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