. Longitudinal study of cerebrospinal fluid levels of tau, A beta1-40, and A beta1-42(43) in Alzheimer's disease: a study in Japan. Ann Neurol. 1998 Jul;44(1):17-26. PubMed.

AlzBiomarker Database

Meta-Analysis

Curated Study Data

Biomarker
(Source)
Cohort
(N)
Measurement
Mean ± SD
Method;
Assay Name;
Manufacturer
Diagnostic
Criteria
Aβ40
(CSF)
AD
(93)
1497.5 ± 827.9
fmol/mL
ELISA;
In-house;
In-house
McKhann et al., 1984
Aβ40
(CSF)
CTRL-
CNC
(41)
1361 ± 858.7
fmol/mL
ELISA;
In-house;
In-house
Aβ42
(CSF)
AD
(93)
109.9 ± 73.2
fmol/mL
ELISA;
In-house;
In-house
McKhann et al., 1984
Aβ42
(CSF)
CTRL-
CNC
(41)
241.7 ± 180.4
fmol/mL
ELISA;
In-house;
In-house
tau-total
(CSF)
AD
(93)
489 ± 297.5
pg/mL
ELISA;
Innotest;
Innogenetics
McKhann et al., 1984
tau-total
(CSF)
CTRL-
CNC
(41)
217.3 ± 128.3
pg/mL
ELISA;
Innotest;
Innogenetics

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This paper appears in the following:

AlzBiomarker

  1. AD vs CTRL : Aβ40 (CSF)
  2. AD vs CTRL : tau-total (CSF)
  3. AD vs CTRL : Aβ42 (CSF)