. Isoform-specific effects of human apolipoprotein E on brain function revealed in ApoE knockout mice: increased susceptibility of females. Proc Natl Acad Sci U S A. 1998 Sep 1;95(18):10914-9. PubMed.


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  1. Experiments involving Tg mice with human gene without the mouse gene will increasingly yeild more clear data like this paper.

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Research Models

  1. NSE-ApoE4
  2. NSE-ApoE3