Zetterberg H, Andreasen N, Blennow K. Increased cerebrospinal fluid levels of transforming growth factor-beta1 in Alzheimer's disease. Neurosci Lett. 2004 Sep 2;367(2):194-6. PubMed.
AlzBiomarker Database
Meta-Analysis
- AD vs CTRL : Aβ42 (CSF)
- CTRL vs AD : Aβ42 (CSF)
- AD vs CTRL : tau-p181 (CSF)
- CTRL vs AD : tau-p181 (CSF)
- AD vs CTRL : tau-total (CSF)
- CTRL vs AD : tau-total (CSF)
Curated Study Data
| Biomarker (Source) |
Cohort (N) |
Measurement Mean ± SD |
Method; Assay Name; Manufacturer |
Diagnostic Criteria |
|---|---|---|---|---|
| Aβ42 (CSF) |
AD (20) |
460 ± 26† pg/mL |
ELISA; Innotest; Innogenetics |
McKhann et al., 1984 |
| Aβ42 (CSF) |
CTRL- CNC (20) |
807 ± 57† pg/mL |
ELISA; Innotest; Innogenetics |
|
| tau-p181 (CSF) |
AD (20) |
104 ± 5.5† pg/mL |
ELISA; Innotest; Innogenetics |
McKhann et al., 1984 |
| tau-p181 (CSF) |
CTRL- CNC (20) |
49 ± 3.3† pg/mL |
ELISA; Innotest; Innogenetics |
|
| tau-total (CSF) |
AD (20) |
1000 ± 71† pg/mL |
ELISA; Innotest; Innogenetics |
McKhann et al., 1984 |
| tau-total (CSF) |
CTRL- CNC (20) |
315 ± 27† pg/mL |
ELISA; Innotest; Innogenetics |
† Mean ± SEM
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