Zhang X, Dong F, Ren J, Driscoll MJ, Culver B.
High dietary fat induces NADPH oxidase-associated oxidative stress and inflammation in rat cerebral cortex.
Exp Neurol. 2005 Feb;191(2):318-25.
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This is an important finding, from experiments on rat tissue, that supports epidemiological evidence to date and suggests related mechanisms for how high levels of dietary fat might weaken cells and lead to dementia, including inflammation.