. Formation of neurofibrillary tangles in P301l tau transgenic mice induced by Abeta 42 fibrils. Science. 2001 Aug 24;293(5534):1491-5. PubMed.

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  1. One of the most important papers of 2001. Along with Lewis, et al.,
    this paper demonstrated a link between Aβ and tau, and importantly
    showed that hyperphosphorylation and aggregation of tau is precipitated
    by Aβ.