Silverman JM, Smith CJ, Marin DB, Mohs RC, Propper CB.
Familial patterns of risk in very late-onset Alzheimer disease.
Arch Gen Psychiatry. 2003 Feb;60(2):190-7.
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I would like to underscore a
point that is made at the end of the paper:
The results of our study suggest that genetic risk factors play a much
smaller role in AD with onset at or after age 85. If so, then this very
late onset group of patients may be an ideal target population in which
to further investigate environmentally mediated risk factors
hypothesized to play a role in AD (e.g. many of the cardiovascular risk factors).
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