. FAD mutants unable to increase neurotoxic Abeta 42 suggest that mutation effects on neurodegeneration may be independent of effects on Abeta. J Neurochem. 2007 May;101(3):674-81. Epub 2007 Jan 24 PubMed.

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Mutations

  1. PSEN1 V82L
  2. PSEN1 Y115H
  3. PSEN1 M139V
  4. PSEN1 M146L (A>C)