. Expression profiling in laser-microdissected hippocampal subregions in rat brain reveals large subregion-specific differences in expression. Eur J Neurosci. 2004 Nov;20(10):2541-54. PubMed.

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  1. This paper emphasizes differential expression of a large number of transcripts in CA3 and dentate gyrus. It appears that the samples that were laser microdissected contained cellular elements in addition to neurons. The authors used in situ hybridization to specify the cellular location of a small sample of transcripts. Ideally, one would like to see available the technology to wed laser capture microdissection of one cell with Affymetrix arrays. Unfortunately, this is not yet implemented.

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