. Evaluation of CSF-tau and CSF-Abeta42 as diagnostic markers for Alzheimer disease in clinical practice. Arch Neurol. 2001 Mar;58(3):373-9. PubMed.

AlzBiomarker Database

Meta-Analysis

Curated Study Data

Biomarker
(Source)
Cohort
(N)
Measurement
Mean ± SD
Method;
Assay Name;
Manufacturer
Diagnostic
Criteria
Aβ42
(CSF)
AD-
Possible Alzheimer's Disease
(58)
572 ± 225
pg/mL
ELISA;
Innotest;
Innogenetics
McKhann et al., 1984
Aβ42
(CSF)
AD-
Probable Alzheimer's Disease
(105)
523 ± 180
pg/mL
ELISA;
Innotest;
Innogenetics
McKhann et al., 1984
Aβ42
(CSF)
CTRL-
Other controls
(18)
897 ± 242
pg/mL
ELISA;
Innotest;
Innogenetics
tau-total
(CSF)
AD-
Possible Alzheimer's Disease
(58)
699 ± 275
pg/mL
ELISA;
Innotest;
Innogenetics
McKhann et al., 1984
tau-total
(CSF)
AD-
Probable Alzheimer's Disease
(105)
759 ± 417
pg/mL
ELISA;
Innotest;
Innogenetics
McKhann et al., 1984
tau-total
(CSF)
CTRL-
Other controls
(18)
264 ± 102
pg/mL
ELISA;
Innotest;
Innogenetics

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