This paper describes a novel mechanism for regulating Ab production. Many in the field often talk about the role of trafficking in APP processing, but this paper provides a nice example where Ab production is modulated via a trafficking mechanism, rather than by a secretase directed mechanism. This emphasizes the potential importance of other agents that modulate trafficking in APP processing.
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Boston University School of Medicine
This paper describes a novel mechanism for regulating Ab production. Many in the field often talk about the role of trafficking in APP processing, but this paper provides a nice example where Ab production is modulated via a trafficking mechanism, rather than by a secretase directed mechanism. This emphasizes the potential importance of other agents that modulate trafficking in APP processing.
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