. Differential levels of p75NTR ectodomain in CSF and blood in patients with Alzheimer's disease: a novel diagnostic marker. Transl Psychiatry. 2015 Oct 6;5:e650. PubMed.

AlzBiomarker Database

Meta-Analysis

Curated Study Data

Biomarker
(Source)
Cohort
(N)
Measurement
Mean ± SD
Method;
Assay Name;
Manufacturer
Diagnostic
Criteria
Aβ40
(CSF)
AD
(25)
367.3 ± 98.4
pg/mL
ELISA;
SIG-38590;
Covance
1993; McKhann et al., 1984
Aβ40
(CSF)
CTRL-
CNC
(26)
392.9 ± 65.1
pg/mL
ELISA;
SIG-38590;
Covance
Aβ40
(Serum)
AD
(156)
86.2 ± 55.5
pg/mL
ELISA;
SIG-38590;
Covance
1993; McKhann et al., 1984
Aβ40
(Serum)
CTRL-
CNC
(129)
60.2 ± 34.7
pg/mL
ELISA;
SIG-38590;
Covance
Aβ42
(CSF)
AD
(25)
243.4 ± 99.9
pg/mL
ELISA;
SIG-38593;
Covance
1993; McKhann et al., 1984
Aβ42
(CSF)
CTRL-
CNC
(26)
425.7 ± 140.5
pg/mL
ELISA;
SIG-38593;
Covance
Aβ42
(Serum)
AD
(156)
68.4 ± 61.9
pg/mL
ELISA;
SIG-38593;
Covance
1993; McKhann et al., 1984
Aβ42
(Serum)
CTRL-
CNC
(129)
49.3 ± 27.7
pg/mL
ELISA;
SIG-38593;
Covance
tau-phospho
(CSF)
AD
(25)
127.5 ± 53.5
pg/mL
ELISA;
KUO0631;
Invitrogen
1993; McKhann et al., 1984
tau-phospho
(CSF)
CTRL-
CNC
(26)
55.4 ± 29.2
pg/mL
ELISA;
KUO0631;
Invitrogen
tau-total
(CSF)
AD
(25)
466.8 ± 231.2
pg/mL
ELISA;
KUB0041;
Invitrogen
1993; McKhann et al., 1984
tau-total
(CSF)
CTRL-
CNC
(26)
325.5 ± 104.7
pg/mL
ELISA;
KUB0041;
Invitrogen
tau-total
(Serum)
AD
(156)
227.1 ± 102.2
pg/mL
ELISA;
KUB0041;
Invitrogen
1993; McKhann et al., 1984
tau-total
(Serum)
CTRL-
CNC
(129)
181 ± 103.2
pg/mL
ELISA;
KUB0041;
Invitrogen

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