Seabrook TJ, Thomas K, Jiang L, Bloom J, Spooner E, Maier M, Bitan G, Lemere CA.
Dendrimeric Abeta1-15 is an effective immunogen in wildtype and APP-tg mice.
Neurobiol Aging. 2007 Jun;28(6):813-23.
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This paper provides further data supporting the idea that immunization with N-terminal Aß peptides is effective at reducing plaque deposition and is associated with lower T cell activation potential, supporting the idea that this approach may provide as safer therapeutic vaccine for AD.
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