Liu RY, Zhou JN, Van Heerikhuize J, Hofman MA, Swaab DF.
Decreased melatonin levels in postmortem cerebrospinal fluid in relation to aging, Alzheimer's disease, and apolipoprotein E-epsilon4/4 genotype.
J Clin Endocrinol Metab. 1999 Jan;84(1):323-7.
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It proves clearly that melatonin is a neurotransmitter which disturbs in AD brain.