. Decreased cerebrospinal fluid Abeta(42) correlates with brain atrophy in cognitively normal elderly. Ann Neurol. 2009 Feb;65(2):176-83. PubMed.

AlzBiomarker Database

Meta-Analysis

Curated Study Data

Biomarker
(Source)
Cohort
(N)
Measurement
Mean ± SD
Method;
Assay Name;
Manufacturer
Diagnostic
Criteria
Aβ1-40
(CSF)
AD
(29)
10613 ± 3787
pg/mL
ELISA;
Other/Not Specified;
In-house
McKhann et al., 1984
Aβ1-40
(CSF)
CTRL-
CNC
(69)
10524 ± 3837
pg/mL
ELISA;
Other/Not Specified;
In-house
Aβ1-40
(Plasma)
AD
(29)
194 ± 81
pg/mL
ELISA;
Other/Not Specified;
In-house
McKhann et al., 1984
Aβ1-40
(Plasma)
CTRL-
CNC
(69)
220 ± 113
pg/mL
ELISA;
Other/Not Specified;
In-house
Aβ1-42
(CSF)
AD
(29)
472 ± 186
pg/mL
ELISA;
Innotest;
Innogenetics
McKhann et al., 1984
Aβ1-42
(CSF)
CTRL-
CNC
(69)
572 ± 208
pg/mL
ELISA;
Innotest;
Innogenetics
Aβ1-42
(Plasma)
AD
(29)
40 ± 44
pg/mL
ELISA;
Other/Not Specified;
In-house
McKhann et al., 1984
Aβ1-42
(Plasma)
CTRL-
CNC
(69)
64 ± 120
pg/mL
ELISA;
Other/Not Specified;
In-house
tau-p181
(CSF)
AD
(29)
82 ± 46
pg/mL
ELISA;
Innotest;
Innogenetics
McKhann et al., 1984
tau-p181
(CSF)
CTRL-
CNC
(69)
61 ± 27
pg/mL
ELISA;
Innotest;
Innogenetics
tau-total
(CSF)
AD
(29)
534 ± 304
pg/mL
ELISA;
Innotest;
Innogenetics
McKhann et al., 1984
tau-total
(CSF)
CTRL-
CNC
(69)
334 ± 180
pg/mL
ELISA;
Innotest;
Innogenetics

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