. CSF amyloid-beta and tau proteins, and cognitive performance, in early and untreated Parkinson's disease: the Norwegian ParkWest study. J Neurol Neurosurg Psychiatry. 2010 Oct;81(10):1080-6. Epub 2010 Jun 14 PubMed.

AlzBiomarker Database

Meta-Analysis

Curated Study Data

Biomarker
(Source)
Cohort
(N)
Measurement
Mean ± SD
Method;
Assay Name;
Manufacturer
Diagnostic
Criteria
Aβx-38
(CSF)
AD
(20)
514 ± 267
pg/mL
Electrochemiluminescence;
MSD 4G8;
Meso Scale Discovery
McKhann et al., 1984
Aβx-38
(CSF)
CTRL-
CNC
(36)
629 ± 332
pg/mL
Electrochemiluminescence;
MSD 4G8;
Meso Scale Discovery
Aβx-40
(CSF)
AD
(20)
6104 ± 1505
pg/mL
Electrochemiluminescence;
MSD 4G8;
Meso Scale Discovery
McKhann et al., 1984
Aβx-40
(CSF)
CTRL-
CNC
(36)
7070 ± 2432
pg/mL
Electrochemiluminescence;
MSD 4G8;
Meso Scale Discovery
Aβx-42
(CSF)
AD
(20)
208 ± 78
pg/mL
Electrochemiluminescence;
MSD 4G8;
Meso Scale Discovery
McKhann et al., 1984
Aβx-42
(CSF)
CTRL-
CNC
(36)
445 ± 223
pg/mL
Electrochemiluminescence;
MSD 4G8;
Meso Scale Discovery
tau-p181
(CSF)
AD
(20)
89 ± 36
pg/mL
ELISA;
Innotest;
Innogenetics
McKhann et al., 1984
tau-p181
(CSF)
CTRL-
CNC
(36)
51 ± 23
pg/mL
ELISA;
Innotest;
Innogenetics
tau-total
(CSF)
AD
(20)
435 ± 217
pg/mL
ELISA;
Innotest;
Innogenetics
McKhann et al., 1984
tau-total
(CSF)
CTRL-
CNC
(36)
228 ± 110
pg/mL
ELISA;
Innotest;
Innogenetics

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