Multhaup G, Ruppert T, Schlicksupp A, Hesse L, Bill E, Pipkorn R, Masters CL, Beyreuther K. Copper-binding amyloid precursor protein undergoes a site-specific fragmentation in the reduction of hydrogen peroxide. Biochemistry. 1998 May 19;37(20):7224-30. PubMed.
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Osaka City University Medical School
This paper is interesting because of a potent relationship between APP metabolism and radical formation on the basis of a site-specific cleavage.
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