Gómez-Tortosa E, Gonzalo I, Fanjul S, Sainz MJ, Cantarero S, Cemillán C, Yébenes JG, del Ser T. Cerebrospinal fluid markers in dementia with lewy bodies compared with Alzheimer disease. Arch Neurol. 2003 Sep;60(9):1218-22. PubMed.
AlzBiomarker Database
Meta-Analysis
- AD vs CTRL : Aβ42 (CSF)
- CTRL vs AD : Aβ42 (CSF)
- DLB vs AD : Aβ42 (CSF)
- AD vs CTRL : tau-total (CSF)
- CTRL vs AD : tau-total (CSF)
- DLB vs AD : tau-total (CSF)
Curated Study Data
| Biomarker (Source) |
Cohort (N) |
Measurement Mean ± SD |
Method; Assay Name; Manufacturer |
Diagnostic Criteria |
|---|---|---|---|---|
| Aβ42 (CSF) |
AD (33) |
348 ± 309 pg/mL |
ELISA; Innotest; Innogenetics |
McKhann et al., 1984 |
| Aβ42 (CSF) |
CTRL- Other Controls (46) |
462 ± 352 pg/mL |
ELISA; Innotest; Innogenetics |
|
| Aβ42 (CSF) |
DLB (25) |
320 ± 233 pg/mL |
ELISA; Innotest; Innogenetics |
McKeith et al., 1996 |
| tau-total (CSF) |
AD (33) |
500 ± 399 pg/mL |
ELISA; Innotest; Innogenetics |
McKhann et al., 1984 |
| tau-total (CSF) |
CTRL- Other Controls (46) |
200 ± 243 pg/mL |
ELISA; Innotest; Innogenetics |
|
| tau-total (CSF) |
DLB (25) |
213 ± 243 pg/mL |
ELISA; Innotest; Innogenetics |
McKeith et al., 1996 |
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