Lanari A, Parnetti L. Cerebrospinal fluid biomarkers and prediction of conversion in patients with mild cognitive impairment: 4-year follow-up in a routine clinical setting. ScientificWorldJournal. 2009 Sep 15;9:961-6. PubMed.

AlzBiomarker Database

Meta-Analysis

Curated Study Data

Biomarker
(Source)		 Cohort
(N)		 Measurement
Mean ± SD		 Method;
Assay Name;
Manufacturer		 Diagnostic
Criteria
Aβ42
(CSF)		 AD
(100)		 411 ± 148
pg/mL		 ELISA;
Innotest;
Innogenetics		 McKhann et al., 1984
Aβ42
(CSF)		 DLB
(14)		 386 ± 142
pg/mL		 ELISA;
Innotest;
Innogenetics		 McKeith et al., 1999
Aβ42
(CSF)		 FTD
(11)		 441 ± 141
pg/mL		 ELISA;
Innotest;
Innogenetics		 1994
Aβ42
(CSF)		 MCI-AD
(18)		 402 ± 195
pg/mL		 ELISA;
Innotest;
Innogenetics		 McKhann et al., 1984
Aβ42
(CSF)		 MCI-Stable
(31)		 942 ± 490
pg/mL		 ELISA;
Innotest;
Innogenetics		 Petersen et al., 1999
tau-p181
(CSF)		 AD
(100)		 136 ± 59
pg/mL		 ELISA;
Innotest;
Innogenetics		 McKhann et al., 1984
tau-p181
(CSF)		 DLB
(14)		 39 ± 21
pg/mL		 ELISA;
Innotest;
Innogenetics		 McKeith et al., 1999
tau-p181
(CSF)		 FTD
(11)		 65 ± 35
pg/mL		 ELISA;
Innotest;
Innogenetics		 1994
tau-p181
(CSF)		 MCI-AD
(18)		 91 ± 31
pg/mL		 ELISA;
Innotest;
Innogenetics		 McKhann et al., 1984
tau-p181
(CSF)		 MCI-Stable
(31)		 40 ± 12
pg/mL		 ELISA;
Innotest;
Innogenetics		 Petersen et al., 1999
tau-total
(CSF)		 AD
(100)		 628 ± 314
pg/mL		 ELISA;
Innotest;
Innogenetics		 McKhann et al., 1984
tau-total
(CSF)		 DLB
(14)		 458 ± 397
pg/mL		 ELISA;
Innotest;
Innogenetics		 McKeith et al., 1999
tau-total
(CSF)		 FTD
(11)		 529 ± 374
pg/mL		 ELISA;
Innotest;
Innogenetics		 1994
tau-total
(CSF)		 MCI-AD
(18)		 402 ± 318
pg/mL		 ELISA;
Innotest;
Innogenetics		 McKhann et al., 1984
tau-total
(CSF)		 MCI-Stable
(31)		 235 ± 230
pg/mL		 ELISA;
Innotest;
Innogenetics		 Petersen et al., 1999

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This paper appears in the following:

AlzBiomarker

  1. DLB vs AD : Aβ42 (CSF)
  2. FTD vs AD : Aβ42 (CSF)
  3. MCI-AD vs MCI-Stable : Aβ42 (CSF)
  4. DLB vs AD : tau-p181 (CSF)
  5. FTD vs AD : tau-p181 (CSF)
  6. MCI-AD vs MCI-Stable : tau-p181 (CSF)
  7. DLB vs AD : tau-total (CSF)
  8. FTD vs AD : tau-total (CSF)
  9. MCI-AD vs MCI-Stable : tau-total (CSF)