. Carnosic acid suppresses the production of amyloid-β 1-42 by inducing the metalloprotease gene TACE/ADAM17 in SH-SY5Y human neuroblastoma cells. Neurosci Res. 2013 Feb;75(2):94-102. PubMed.


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  1. This paper opens a new way to fight AD. It breaks the paradigm in the sense that upregulating, but not inhibiting, presenilin leads to decreased Aβ42 levels.

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