. The brain injury biomarker VLP-1 is increased in the cerebrospinal fluid of Alzheimer disease patients. Clin Chem. 2008 Oct;54(10):1617-23. Epub 2008 Aug 14 PubMed.

AlzBiomarker Database

Meta-Analysis

Curated Study Data

Biomarker
(Source)
Cohort
(N)
Measurement
Mean ± SD
Method;
Assay Name;
Manufacturer
Diagnostic
Criteria
Aβ1-42
(CSF)
AD
(33)
471 ± 172
ng/mL §
ELISA;
Innotest;
Innogenetics
McKhann et al., 1984
Aβ1-42
(CSF)
CTRL-
CNC
(24)
698 ± 230
ng/mL §
ELISA;
Innotest;
Innogenetics
VLP-1
(CSF)
AD
(33)
387 ± 157
pg/mL §
ELISA;
Other/Not Specified;
In-house
McKhann et al., 1984
VLP-1
(CSF)
CTRL-
CNC
(24)
234 ± 101
pg/mL §
ELISA;
Other/Not Specified;
In-house
tau-p181
(CSF)
AD
(33)
100 ± 40
ng/mL §
ELISA;
Innotest;
Innogenetics
McKhann et al., 1984
tau-p181
(CSF)
CTRL-
CNC
(24)
61 ± 29
ng/mL §
ELISA;
Innotest;
Innogenetics
tau-total
(CSF)
AD
(33)
735 ± 443
ng/mL §
ELISA;
Innotest;
Innogenetics
McKhann et al., 1984
tau-total
(CSF)
CTRL-
CNC
(24)
395 ± 204
ng/mL §
ELISA;
Innotest;
Innogenetics

§ Data supplied to Alzforum by author

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