. Amyloid-β oligomers in cerebrospinal fluid are associated with cognitive decline in patients with Alzheimer's disease. J Alzheimers Dis. 2012;29(1):171-6. PubMed.

AlzBiomarker Database

Meta-Analysis

Curated Study Data

Biomarker
(Source)
Cohort
(N)
Measurement
Mean ± SD
Method;
Assay Name;
Manufacturer
Diagnostic
Criteria
Aβ42
(CSF)
AD
(14)
262.1 ± 42.1
pg/mL
ELISA;
Innotest;
Innogenetics
McKhann et al., 1984
Aβ42
(CSF)
CTRL-
Other Controls
(12)
685 ± 175.2
pg/mL
ELISA;
Innotest;
Innogenetics
tau-p181
(CSF)
AD
(14)
122.2 ± 28.4
pg/mL
ELISA;
Innotest;
Innogenetics
McKhann et al., 1984
tau-p181
(CSF)
CTRL-
Other Controls
(12)
40.4 ± 10.8
pg/mL
ELISA;
Innotest;
Innogenetics
tau-total
(CSF)
AD
(14)
942.8 ± 216.5
pg/mL
ELISA;
Innotest;
Innogenetics
McKhann et al., 1984
tau-total
(CSF)
CTRL-
Other Controls
(12)
253.3 ± 77.1
pg/mL
ELISA;
Innotest;
Innogenetics

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