. Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory. Nat Med. 2008 Aug;14(8):837-42. PubMed.


Please login to recommend the paper.


Make a Comment

Comments on this Paper

  1. After plaques, protofibrils, Aβ42, it is suggested that the killer is the dimer. How can we reconcile this in vitro finding with neuropathological observations of non-demented patients with widespread and huge Aβ aggregates (not plaque cores) in the neocortex?

Make a Comment

To make a comment you must login or register.