. An Alzheimer's disease-linked PS1 variant rescues the developmental abnormalities of PS1-deficient embryos. Neuron. 1998 Mar;20(3):603-9. PubMed.

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  1. This study is extremely important to show some basic property of presenilin-1. It is a remarkable point that the levels of Abeta 1-42/43 and A beta 1-40 peptides between PS1(+/-) and control mice are indistinguishable.

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