Blacker D, Wilcox MA, Laird NM, Rodes L, Horvath SM, Go RC, Perry R, Watson B, Bassett SS, McInnis MG, Albert MS, Hyman BT, Tanzi RE.
Alpha-2 macroglobulin is genetically associated with Alzheimer disease.
Nat Genet. 1998 Aug;19(4):357-60.
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A2M is claimed to be associated with AD using some AD cases. It is rational from the considerable amount of evidence accumulated by neuropathologists. The story is not new but its impact is significant.
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