. Allopregnanolone reverses neurogenic and cognitive deficits in mouse model of Alzheimer's disease. Proc Natl Acad Sci U S A. 2010 Apr 6;107(14):6498-503. PubMed.


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  1. I suggest reading the excellent Alzforum news article by Tom Fagan on our findings regarding the efficacy of allopregnanolone to reverse neurogenic and cognitive deficits in the 3xTgAD male mouse in PNAS and hyperphosphorylated tau in neural progenitor cells reported by Orly Lazarov and colleagues.