Alzforum: Papers of the Week

Khandai AC, Aizenstein HJ. Recent advances in neuroimaging biomarkers in geriatric psychiatry. Curr Psychiatry Rep. 2013 Jun;15(6):360. PubMed Abstract

Petiau C, Onen H, Delgado A, Touchon J. Exploring sleep-related outcomes in patients with mild to moderate Alzheimer's disease initiating acetylcholinesterase inhibitor therapy: the Morpheus survey. Int J Geriatr Psychiatry. 2013 Jun;28(6):657-9. PubMed Abstract

Klebe S, Golmard JL, Nalls MA, Saad M, Singleton AB, Bras JM, Hardy J, Simon-Sanchez J, Heutink P, Kuhlenbäumer G, Charfi R, Klein C, Hagenah J, Gasser T, Wurster I, Lesage S, Lorenz D, Deuschl G, Durif F, Pollak P, Damier P, Tison F, Durr A, Amouyel P, Lambert JC. The Val158Met COMT polymorphism is a modifier of the age at onset in Parkinson's disease with a sexual dimorphism. J Neurol Neurosurg Psychiatry. 2013 Jun;84(6):666-73. PubMed Abstract

Im HJ, Won Hwang D, Kyu Lee H, Jang J, Lee S, Youn H, Jin Y, Kim SU, Edmund Kim E, Sik Kim Y, Soo Lee D. In vivo visualization and monitoring of viable neural stem cells using noninvasive bioluminescence imaging in the 6-hydroxydopamine-induced mouse model of Parkinson disease. Mol Imaging. 2013 Jun 1;12(4):224-34. PubMed Abstract

Ostapchenko VG, Beraldo FH, Guimarães AL, Mishra S, Guzman M, Fan J, Martins VR, Prado VF, Prado MA. Increased prion protein processing and expression of metabotropic glutamate receptor 1 in a mouse model of Alzheimer's disease. J Neurochem. 2013 May 8; PubMed Abstract

Hultman K, Strickland S, Norris EH. The APOE ɛ4/ɛ4 genotype potentiates vascular fibrin(ogen) deposition in amyloid-laden vessels in the brains of Alzheimer's disease patients. J Cereb Blood Flow Metab. 2013 May 8; PubMed Abstract

Du X, Li H, Wang Z, Qiu S, Liu Q, Ni J. Selenoprotein P and selenoprotein M block Zn(2+)-mediated Aβ42 aggregation and toxicity. Metallomics. 2013 May 8; PubMed Abstract

Todd S, Barr S, Passmore AP. Cause of death in Alzheimer's disease: a cohort study. QJM. 2013 May 7; PubMed Abstract

Pfeifer L, Drobetz R, Fankhauser S, Mortby ME, Maercker A, Forstmeier S. Caregiver rating bias in mild cognitive impairment and mild Alzheimer's disease: impact of caregiver burden and depression on dyadic rating discrepancy across domains. Int Psychogeriatr. 2013 May 7;:1-11. PubMed Abstract

Ma Q, An X, Li Z, Zhang H, Huang W, Cai L, Hu P, Lin Q, Tzeng CM. P268S in NOD2 associates with susceptibility to Parkinson's disease in Chinese population. Behav Brain Funct. 2013 May 7;9(1):19. PubMed Abstract

Sato M, Murakami K, Uno M, Ikubo H, Nakagawa Y, Katayama S, Akagi KI, Irie K. Structure-Activity Relationship for (+)-Taxifolin Isolated from Silymarin as an Inhibitor of Amyloid β Aggregation. Biosci Biotechnol Biochem. 2013 May 7; PubMed Abstract

Yuan YH, Sun JD, Wu MM, Hu JF, Peng SY, Chen NH. Rotenone Could Activate Microglia Through NFκB Associated Pathway. Neurochem Res. 2013 May 7; PubMed Abstract

Yu L, Boyle P, Schneider JA, Segawa E, Wilson RS, Leurgans S, Bennett DA. APOE ε4, Alzheimer's Disease Pathology, Cerebrovascular Disease, and Cognitive Change Over the Years Prior to Death. Psychol Aging. 2013 May 6; PubMed Abstract

Nascimento CM, Ayan C, Cancela JM, Gobbi LT, Gobbi S, Stella F. Effect of a multimodal exercise program on sleep disturbances and instrumental activities of daily living performance on Parkinson's and Alzheimer's disease patients. Geriatr Gerontol Int. 2013 May 6; PubMed Abstract

Gauthier S, Robillard A, Cohen S, Black S, Sampalis J, Colizza D, de Takacsy F, Schecter R, on behalf of the EMBRACE investigators. Real-life effectiveness and tolerability of rivastigmine transdermal patch in patients with mild-to-moderate Alzheimer's disease: The EMBRACE study. Curr Med Res Opin. 2013 May 6; PubMed Abstract

Wilkins CH, Roe CM, Morris JC, Galvin JE. Mild Physical Impairment Predicts Future Diagnosis of Dementia of the Alzheimer's Type. J Am Geriatr Soc. 2013 May 6; PubMed Abstract

Rana A, Rera M, Walker DW. Parkin overexpression during aging reduces proteotoxicity, alters mitochondrial dynamics, and extends lifespan. Proc Natl Acad Sci U S A. 2013 May 6; PubMed Abstract

Li M, Xu C, Wu L, Ren J, Wang E, Qu X. Self-Assembled Peptide-Polyoxometalate Hybrid Nanospheres: Two in One Enhances Targeted Inhibition of Amyloid β-Peptide Aggregation Associated with Alzheimer's Disease. Small. 2013 May 6; PubMed Abstract

Lawrence V, Pickett J, Ballard C, Murray J. Patient and carer views on participating in clinical trials for prodromal Alzheimer's disease and mild cognitive impairment. Int J Geriatr Psychiatry. 2013 May 6; PubMed Abstract

Cosentino S, Schupf N, Christensen K, Andersen SL, Newman A, Mayeux R. Reduced Prevalence of Cognitive Impairment in Families With Exceptional Longevity. JAMA Neurol. 2013 May 6;:1-8. PubMed Abstract

Mora N, Santa Bárbara P, Ferreira N, Serras F. Ras signal triggers β-Amyloid Precursor Protein (APP) expression. Small GTPases. 2013 May 6;4(3) PubMed Abstract

Kepe V, Moghbel MC, Långström B, Zaidi H, Vinters HV, Huang SC, Satyamurthy N, Doudet D, Mishani E, Cohen RM, Høilund-Carlsen PF, Alavi A, Barrio JR. Amyloid-β Positron Emission Tomography Imaging Probes: A Critical Review. J Alzheimers Dis. 2013 May 6; PubMed Abstract

Saydoff JA, Olariu A, Sheng J, Hu Z, Li Q, Garcia R, Pei J, Sun GY, von Borstel R. Uridine Prodrug Improves Memory in Tg2576 and TAPP Mice and Reduces Pathological Factors associated with Alzheimer's Disease in Related Models. J Alzheimers Dis. 2013 May 6; PubMed Abstract

Jefferson AL, Lambe S, Romano R, Liu D, Islam F, Kowall N. An Intervention to Enhance Alzheimer's Disease Clinical Research Participation among Older African Americans. J Alzheimers Dis. 2013 May 6; PubMed Abstract

Sun F, Mao X, Xie L, Greenberg DA, Jin K. Neuroglobin Protein is Upregulated in Alzheimer's Disease. J Alzheimers Dis. 2013 May 6; PubMed Abstract