Santuccione AC, Merlini M, Shetty A, Tackenberg C, Bali J, Ferretti MT, McAfoose J, Kulic L, Bernreuther C, Welt T, Grimm J, Glatzel M, Rajendran L, Hock C, Nitsch RM.
Active vaccination with ankyrin G reduces β-amyloid pathology in APP transgenic mice. Mol Psychiatry .
2013 Mar;18(3):358-68.
PubMed Abstract
Cullen VC, Fredenburg RA, Evans C, Conliffe PR, Solomon ME.
Development and advanced validation of an optimized method for the quantitation of aβ(42) in human cerebrospinal fluid. AAPS J .
2012 Sep;14(3):510-8.
PubMed Abstract
Vardarajan BN, Bruesegem SY, Harbour ME, St George-Hyslop P, Seaman MN, Farrer LA.
Identification of Alzheimer disease-associated variants in genes that regulate retromer function. Neurobiol Aging .
2012 Sep;33(9):2231.e15-2231.e30.
PubMed Abstract
Zhou L, Barão S, Laga M, Bockstael K, Borgers M, Gijsen H, Annaert W, Moechars D, Mercken M, Gevaert K, Gevaer K, De Strooper B.
The neural cell adhesion molecules L1 and CHL1 are cleaved by BACE1 protease in vivo. J Biol Chem .
2012 Jul 27;287(31):25927-40.
PubMed Abstract
Schöll M, Wall A, Thordardottir S, Ferreira D, Bogdanovic N, Långström B, Almkvist O, Graff C, Nordberg A.
Low PiB PET retention in presence of pathologic CSF biomarkers in Arctic APP mutation carriers. Neurology .
2012 Jul 17;79(3):229-36.
PubMed Abstract
Krishnan R, Goodman JL, Mukhopadhyay S, Pacheco CD, Lemke EA, Deniz AA, Lindquist S.
Conserved features of intermediates in amyloid assembly determine their benign or toxic states. Proc Natl Acad Sci U S A .
2012 Jul 10;109(28):11172-7.
PubMed Abstract
Prince M, Acosta D, Ferri CP, Guerra M, Huang Y, Llibre Rodriguez JJ, Salas A, Sosa AL, Williams JD, Dewey ME, Acosta I, Jotheeswaran AT, Liu Z.
Dementia incidence and mortality in middle-income countries, and associations with indicators of cognitive reserve: a 10/66 Dementia Research Group population-based cohort study. Lancet .
2012 Jul 7;380(9836):50-8.
PubMed Abstract
Winblad B, Andreasen N, Minthon L, Floesser A, Imbert G, Dumortier T, Maguire RP, Blennow K, Lundmark J, Staufenbiel M, Orgogozo JM, Graf A.
Safety, tolerability, and antibody response of active Aβ immunotherapy with CAD106 in patients with Alzheimer's disease: randomised, double-blind, placebo-controlled, first-in-human study. Lancet Neurol .
2012 Jul;11(7):597-604.
PubMed Abstract
Bhalla A, Vetanovetz CP, Morel E, Chamoun Z, Di Paolo G, Small SA.
The location and trafficking routes of the neuronal retromer and its role in amyloid precursor protein transport. Neurobiol Dis .
2012 Jul;47(1):126-34.
PubMed Abstract
Limon A, Reyes-Ruiz JM, Miledi R.
Loss of functional GABA(A) receptors in the Alzheimer diseased brain. Proc Natl Acad Sci U S A .
2012 Jun 19;109(25):10071-6.
PubMed Abstract
Damoiseaux JS, Seeley WW, Zhou J, Shirer WR, Coppola G, Karydas A, Rosen HJ, Miller BL, Kramer JH, Greicius MD, Alzheimer's Disease Neuroimaging Initiative.
Gender modulates the APOE ε4 effect in healthy older adults: convergent evidence from functional brain connectivity and spinal fluid tau levels. J Neurosci .
2012 Jun 13;32(24):8254-62.
PubMed Abstract
Vanderweyde T, Yu H, Varnum M, Liu-Yesucevitz L, Citro A, Ikezu T, Duff K, Wolozin B.
Contrasting pathology of the stress granule proteins TIA-1 and G3BP in tauopathies. J Neurosci .
2012 Jun 13;32(24):8270-83.
PubMed Abstract
William CM, Andermann ML, Goldey GJ, Roumis DK, Reid RC, Shatz CJ, Albers MW, Frosch MP, Hyman BT.
Synaptic plasticity defect following visual deprivation in Alzheimer’s disease model transgenic mice. J Neurosci .
2012 June 6;32(23):8004-11.
Abstract
Brouillette J, Caillierez R, Zommer N, Alves-Pires C, Benilova I, Blum D, De Strooper B, Buée L.
Neurotoxicity and memory deficits induced by soluble low-molecular-weight amyloid-β1-42 oligomers are revealed in vivo by using a novel animal model. J Neurosci .
2012 Jun 6;32(23):7852-61.
PubMed Abstract
Barrett PJ, Song Y, Van Horn WD, Hustedt EJ, Schafer JM, Hadziselimovic A, Beel AJ, Sanders CR.
The amyloid precursor protein has a flexible transmembrane domain and binds cholesterol. Science .
2012 Jun 1;336(6085):1168-71.
PubMed Abstract
Nussbaum JM, Schilling S, Cynis H, Silva A, Swanson E, Wangsanut T, Tayler K, Wiltgen B, Hatami A, Rönicke R, Reymann K, Hutter-Paier B, Alexandru A, Jagla W, Graubner S, Glabe CG, Demuth HU, Bloom GS.
Prion-like behaviour and tau-dependent cytotoxicity of pyroglutamylated amyloid-β. Nature .
2012 May 31;485(7400):651-5.
PubMed Abstract
Busche MA, Chen X, Henning HA, Reichwald J, Staufenbiel M, Sakmann B, Konnerth A.
Critical role of soluble amyloid-β for early hippocampal hyperactivity in a mouse model of Alzheimer's disease. Proc Natl Acad Sci U S A .
2012 May 29;109(22):8740-5.
PubMed Abstract
Zhang X, Hoey RJ, Lin G, Koide A, Leung B, Ahn K, Dolios G, Paduch M, Ikeuchi T, Wang R, Li YM, Koide S, Sisodia SS.
Identification of a tetratricopeptide repeat-like domain in the nicastrin subunit of γ-secretase using synthetic antibodies. Proc Natl Acad Sci U S A .
2012 May 29;109(22):8534-9.
PubMed Abstract
Bell RD, Winkler EA, Singh I, Sagare AP, Deane R, Wu Z, Holtzman DM, Betsholtz C, Armulik A, Sallstrom J, Berk BC, Zlokovic BV.
Apolipoprotein E controls cerebrovascular integrity via cyclophilin A. Nature .
2012 May 24;485(7399):512-6.
PubMed Abstract
Bakker A, Krauss GL, Albert MS, Speck CL, Jones LR, Stark CE, Yassa MA, Bassett SS, Shelton AL, Gallagher M.
Reduction of hippocampal hyperactivity improves cognition in amnestic mild cognitive impairment. Neuron .
2012 May 10;74(3):467-74.
PubMed Abstract
Mohamed A, Saavedra L, Di Pardo A, Sipione S, Posse de Chaves E.
β-amyloid inhibits protein prenylation and induces cholesterol sequestration by impairing SREBP-2 cleavage. J Neurosci .
2012 May 9;32(19):6490-500.
PubMed Abstract
Smith GS, Laxton AW, Tang-Wai DF, McAndrews MP, Diaconescu AO, Workman CI, Lozano AM.
Increased Cerebral Metabolism After 1 Year of Deep Brain Stimulation in Alzheimer Disease. Arch Neurol .
2012 May 7;
PubMed Abstract
Boyle PA, Buchman AS, Wilson RS, Yu L, Schneider JA, Bennett DA.
Effect of purpose in life on the relation between Alzheimer disease pathologic changes on cognitive function in advanced age. Arch Gen Psychiatry .
2012 May;69(5):499-505.
PubMed Abstract
Barnes DE, Yaffe K, Byers AL, McCormick M, Schaefer C, Whitmer RA.
Midlife vs late-life depressive symptoms and risk of dementia: differential effects for Alzheimer disease and vascular dementia. Arch Gen Psychiatry .
2012 May;69(5):493-8.
PubMed Abstract
Verret L, Mann EO, Hang GB, Barth AM, Cobos I, Ho K, Devidze N, Masliah E, Kreitzer AC, Mody I, Mucke L, Palop JJ.
Inhibitory interneuron deficit links altered network activity and cognitive dysfunction in Alzheimer model. Cell .
2012 Apr 27;149(3):708-21.
PubMed Abstract
Home
Check out our upcoming Webinar: 
