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Vincent I. on PAPER: Yang Y. et al., 2006, In the last few years, Karl Herrup's group has steadfastly and beautifully expounded on the... 25 Jan 2006.
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Vincent I. on NEWS: Inflammation Boosts Brain CDK5 Activity, Tau Phosphorylation, Elevated p25 is thought to account for increased or pathological CDK5 activation that seems to... 6 Oct 2005.
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Vincent I. on PAPER: Lim AC. et al., 2004, This is a beautifully done study and is timely. It will and should shift the
focus in the field... 9 Sep 2004.
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Vincent I. on NEWS: Caught in the Act: NPC1 Found to Bind Cholesterol, Because of the accumulation of cholesterol in NPC patients having mutated NPC1, it has been... 30 Aug 2004.
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Vincent I. on NEWS: Herpes and AD—Virus Hitches Ride with APP, The presence of HSV in brain has been correlated previously with Alzheimer's disease ( 19 Nov 2003.
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Vincent I. on PAPER: Gärtner U. et al., 2003, I am submitting this invited comment with the caveat that I have not had an opportunity to read... 28 Aug 2003.
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Vincent I. on NEWS: Linking APP with Cell Cycle Reentry and Apoptosis—One Kinase Does the Trick, McPhie et al. have done a beautiful job unraveling the signaling pathway linking FAD mutants of... 18 Aug 2003.
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Vincent I. on NEWS: Lithium Hinders Aβ Generation, Buffing Up GSK as Drug Target, I have never understood why GSK3α was neglected in studies of Alzheimer's neurodegeneration for... 23 May 2003.
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Vincent I. on PAPER: Rideout HJ. et al., 2003, This is an excellent study that delineates the precise role of cdks in neuronal death using a... 19 Apr 2003.
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Vincent I. on PAPER: Nguyen MD. et al., 2003, This is a very interesting finding, and complements nicely the paper by 19 Apr 2003.
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Vincent I. on NEWS: AD Cell Cycle Reentry—Early Rather Than Late, This paper stands apart from amongst the swath of papers that describe changes in AD brain as a... 16 Apr 2003.
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Vincent I. on PAPER: Bodor N. et al., 2002, This sounds fascinating! I can't wait to learn more about CDSs, and perhaps experiment with them! 6 Feb 2003.
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Vincent I. on PAPER: Okawa Y. et al., 2003, The abstract for this paper does not adequately describe the findings of this work or their... 6 Feb 2003.
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Vincent I. on PAPER: Li G. et al., 2003, The conversion of p35 to p25 has been implicated as the underlying cause of cdk5 hyperactivation... 6 Feb 2003.
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Vincent I. on PAPER: Hamdane M. et al., 2002, This work is a nice adjunct to the Bioessays review by Lu et al (Feb 2003). Animal models of... 29 Jan 2003.
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Vincent I. on PAPER: Ohkubo N. et al., 2003, This is a beautiful study aimed at unraveling the connection between ApoE, a prominent risk... 17 Jan 2003.
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Vincent I. on PAPER: El-Khodor BF. et al., 2003, This is a fascinating study that uses an in vivo model to explore the role of cell cycle... 17 Jan 2003.
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Vincent I. on NEWS: Oxidative Stress Triggers Neuronal Cell-Cycle Reentry, I loved this paper.This work makes a compelling case for the involvement of oxidative stress in... 26 Sep 2002.
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Vincent I. on NEWS: p53 as Mediator of Oxidative Stress and Inflammation?, The problem of p53 mutations leading to clonal expansion and hence exacerbation of inflammation... 24 Aug 2002.
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Vincent I. on PAPER: Hoozemans JJ. et al., 2002, This is a nice paper that ties together inflammation and the cell cycle in AD. Although the... 15 Aug 2002.
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Vincent I. on PAPER: Martín-Aparicio E. et al., 2002, This is a lovely piece of work reporting that the specific nuclear localization of mutant htt... 14 Aug 2002.
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Vincent I. on PAPER: Town T. et al., 2002, In response to the comment by Tan, et al.:
The use of primary rat neurons in Tsai's study... 1 Aug 2002.
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Vincent I. on PAPER: Morrison JH. et al., 2002, Recommendation Only. 1 Aug 2002.
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Vincent I. on PAPER: Town T. et al., 2002, This study is signficant because it demonstrates that soluble extracellular Aβ can cause cdk5... 24 Jul 2002.
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Vincent I. on PAPER: Wyss-Coray T. et al., 2002, This paper is clealry of importance because of the prominent neurodegeneration induced by... 24 Jul 2002.
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Vincent I. on PAPER: Morris EJ. et al., 2001, This report is a continuation of a series of papers in which Dr Park and his colleagues attempt... 4 Jul 2002.
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Vincent I. on PAPER: Kins S. et al., 2001, Kins et al, have done an important study on a rather neglected aspect of AD pathology, ie, the... 29 Jun 2002.
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Vincent I. on PAPER: Kordower JH. et al., 2001, Does this imply that atrophy and loss of layer II entorhinal cortex neurons are not part of the... No date saved.
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Vincent I. on PAPER: Chen M. et al., 2001, Would the diagnosis for a 90 year old individual with grey hair and wrinkles but no tangles and... No date saved.
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Vincent I. on PAPER: García-Sierra F. et al., 2001, The MC1 antibody produced by Dr Peter Davies may be more sensitive than Alz-50 for tracing early... No date saved.
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