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1 to 30 of 53 results |
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Van Leuven F. on NEWS: Does ApoE4 Lower Brain Metabolism Independently of Aβ?, I daresay, "most intriguing" (referring to the famous Belgian Janssen twins). This could add... 17 Dec 2012.
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Van Leuven F. on NEWS: Bapineuzumab Phase 3: Target Engagement, But No Benefit, It is still amazing how many scientists in this field want to believe instead of look at facts... 4 Oct 2012.
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Van Leuven F. on NEWS: Honolulu: The Missing Link? Tau Mediates Aβ Toxicity at Synapse, I agree with Lennart Mucke, Akihiko Takashima, and Michel Goedert that this is a major opus by... 12 Aug 2010.
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Van Leuven F. on PAPER: Decker H. et al., 2010, I agree with the three previous commentators that the levels of Aβ used in these experiments are... 9 Aug 2010.
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Van Leuven F. on PAPER: Feuillette S. et al., 2010, Agreed and supported by our AAV-tau models; see reference below. 18 Mar 2010.
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Van Leuven F. on NEWS: Paper Alert—Phase 3 Tarenflurbil Data Published, It's amazing to have to read the "blame it on the mouse models" excuse.
Those working with... 14 Jan 2010.
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Van Leuven F. on SITE POLL: Would you get tested for your ApoE genotype?, The first line of the reaction of Mr./Ms. A. Anonymous should read:
“A funny thing... 1 Dec 2009.
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Van Leuven F. on NEWS: New Triple Transgenic Shows Mitochondrial Damage by Tau, Aβ, The typical feature of AD, i.e., memory loss, is irreversible. In contrast "selective memory... 12 Nov 2009.
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Van Leuven F. on PAPER: Saxena S. et al., 2009, While appreciating the impressive FALS study by Sexena et al., I could not help frowning on the... 22 Apr 2009.
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Van Leuven F. on NEWS: Axonal Transport Not Bothered by Tau Elevation In Vivo, The picture is more complicated than the title of Yuan et al. would lead us to believe. Our... 19 Feb 2008.
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Van Leuven F. on NEWS: Imaging Tau and Caspases, Aβ’s Synaptic Effects, The link among activated caspases, tangles, and death of neurons has been proposed based on... 4 Feb 2008.
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Van Leuven F. on NEWS: Enabling Technologies for Alzheimer Disease Research: Seventh Bar Harbor Workshop, 2007, Part 5, I appreciate many, not all, of the items in the list of... 8 Jan 2008.
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Van Leuven F. on LIVE DISCUSSION: The Microglia-dependent Repair Response and Alzheimer΄s Disease Therapy, A most timely topic and discussion, but one with several "open angles."
One is the very... 5 Dec 2007.
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Van Leuven F. on NEWS: Hot Stuff—PIB News From the Pacific Rim, Besides the interesting issues already discussed at length and in depth, the data bring to mind... 30 Oct 2007.
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Van Leuven F. on NEWS: First Crystal Structure of Monoclonal Antibody Binding to Aβ, I agree with Charles and Beka that this is excellent work. It's actually long overdue in the AD... 9 Oct 2007.
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Van Leuven F. on NEWS: Alzhemed Tangles with Tau, Too, Lest this become the "Jurgen Gotz solo" stage, I'd like to sound my three notes:
First, to... 24 Sep 2007.
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Van Leuven F. on PAPER: Conrad C. et al., 2007, Not sure I can share the enthusiasm:
the differences between Normal and AD are no more than a... 18 Sep 2007.
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Van Leuven F. on PAPER: Ring S. et al., 2007, I stand in awe of this painstaking, comprehensive study from Ulrike Müller and coworkers. This... 21 Aug 2007.
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Van Leuven F. on PAPER: Jellinger KA. et al., 2007, I proposed (ICAD-2006, Madrid) that intracerebral bleedings observed in some amyloid mouse... 13 Aug 2007.
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Van Leuven F. on PAPER: Rockenstein E. et al., 2007, My initial enthusiasm, shared with commentator Tom Fagan, for this study was cooled when I tried... 21 Mar 2007.
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Van Leuven F. on NEWS: How Now, Phospho-tau? Sparing Synapses, Messing with Microtubules, While this study helps us to understand some of the actions of tau, several questions come to... 6 Jun 2006.
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Van Leuven F. on LIVE DISCUSSION: Gain or Loss of Function—Time to Shake up Assumptions on γ-Secretase in Alzheimer Disease?, One could fill many more pages with discussions on this topic, pro and con the different theses.... 1 Jun 2006.
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Van Leuven F. on NEWS: Early Events in AD Mice as Targets for Therapy, The first sentence of Pat McCaffrey's news summary is both enlightening and puzzling: "Alzheimer... 27 Mar 2006.
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Dewachter I, Terwel D, Van Leuven F. on NEWS: Is Motor Neuron Axonopathy behind Movement Problems in Alzheimer Disease?, The paper by Oliver Wirths in the group of Thomas Bayer is another instance connecting amyloid... 18 Mar 2006.
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Van Leuven F. on PAPER: Kojro E. et al., 2006, Activation of α-secretase activity to increase non-amyloidogenic processing of APP is definitely... 23 Jan 2006.
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Van Leuven F. on NEWS: SfN: Return of the Other—Tau Is Back, Part 4, One should not forget my favorite natural anti-oxidant, currently being tested in a limited... 19 Dec 2005.
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Dewachter I, Van Leuven F. on LIVE DISCUSSION: Messing with the Membrane—An Alternative Interpretation of the Amyloid-β Hypothesis, The 12 Faces of Amyloid
The problem of the amyloid peptides always reminds us of an... 7 Oct 2005.
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Dewachter I, Van Leuven F. on PAPER: Marchesi VT. et al., 2005, The 12 Faces of Amyloid
The problem of the amyloid peptides always reminds us of an... 7 Oct 2005.
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Van Leuven F. on NEWS: Amyloid Hypothesis—Closing the Spigot Helps, Temporarily, It is very satisfying to see a totally independent confirmation of our work, especially when... 28 Jul 2005.
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Van Leuven F. on NEWS: The Theology of Aβ: Presenilins Giveth, and They Taketh Away, The results reported by Raphaelle Pardossi-Piquard and colleagues are most interesting and also... 31 May 2005.
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1 to 30 of 53 results |
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The ALS Forum is a web-based collaborative effort to bring together valuable ALS-related resources for use by researchers worldwide in both academia and industry-based settings.
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Should the FDA be allowed to use data from overseas clinical trials? |
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Absolutely, we are running out of viable subjects in the U.S. |
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 9 |
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Yes, so long as the data is reliable |
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No, the trials are not as rigorous |
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No, the data should be repeated in the U.S. |
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5 |
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No, the drug sponsors are just trying to cut corners |
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Responses: 51 |
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