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Search Results: Comments By= Van Leuven, Fred; Sort By= Posted Date
1 to 30 of 53 results
Van Leuven F. on NEWS: Does ApoE4 Lower Brain Metabolism Independently of Aβ?, I daresay, "most intriguing" (referring to the famous Belgian Janssen twins). This could add... 17 Dec 2012. 

Van Leuven F. on NEWS: Bapineuzumab Phase 3: Target Engagement, But No Benefit, It is still amazing how many scientists in this field want to believe instead of look at facts... 4 Oct 2012. 

Van Leuven F. on NEWS: Honolulu: The Missing Link? Tau Mediates Aβ Toxicity at Synapse, I agree with Lennart Mucke, Akihiko Takashima, and Michel Goedert that this is a major opus by... 12 Aug 2010. 

Van Leuven F. on PAPER: Decker H. et al., 2010, I agree with the three previous commentators that the levels of Aβ used in these experiments are... 9 Aug 2010. 

Van Leuven F. on PAPER: Feuillette S. et al., 2010, Agreed and supported by our AAV-tau models; see reference below. 18 Mar 2010. 

Van Leuven F. on NEWS: Paper Alert—Phase 3 Tarenflurbil Data Published, It's amazing to have to read the "blame it on the mouse models" excuse. Those working with... 14 Jan 2010. 

Van Leuven F. on SITE POLL: Would you get tested for your ApoE genotype?, The first line of the reaction of Mr./Ms. A. Anonymous should read: “A funny thing... 1 Dec 2009. 

Van Leuven F. on NEWS: New Triple Transgenic Shows Mitochondrial Damage by Tau, Aβ, The typical feature of AD, i.e., memory loss, is irreversible. In contrast "selective memory... 12 Nov 2009. 

Van Leuven F. on PAPER: Saxena S. et al., 2009, While appreciating the impressive FALS study by Sexena et al., I could not help frowning on the... 22 Apr 2009. 

Van Leuven F. on NEWS: Axonal Transport Not Bothered by Tau Elevation In Vivo, The picture is more complicated than the title of Yuan et al. would lead us to believe. Our... 19 Feb 2008. 

Van Leuven F. on NEWS: Imaging Tau and Caspases, Aβ’s Synaptic Effects, The link among activated caspases, tangles, and death of neurons has been proposed based on... 4 Feb 2008. 

Van Leuven F. on NEWS: Enabling Technologies for Alzheimer Disease Research: Seventh Bar Harbor Workshop, 2007, Part 5, I appreciate many, not all, of the items in the list of... 8 Jan 2008. 

Van Leuven F. on LIVE DISCUSSION: The Microglia-dependent Repair Response and Alzheimer΄s Disease Therapy, A most timely topic and discussion, but one with several "open angles." One is the very... 5 Dec 2007. 

Van Leuven F. on NEWS: Hot Stuff—PIB News From the Pacific Rim, Besides the interesting issues already discussed at length and in depth, the data bring to mind... 30 Oct 2007. 

Van Leuven F. on NEWS: First Crystal Structure of Monoclonal Antibody Binding to Aβ, I agree with Charles and Beka that this is excellent work. It's actually long overdue in the AD... 9 Oct 2007. 

Van Leuven F. on NEWS: Alzhemed Tangles with Tau, Too, Lest this become the "Jurgen Gotz solo" stage, I'd like to sound my three notes: First, to... 24 Sep 2007. 

Van Leuven F. on PAPER: Conrad C. et al., 2007, Not sure I can share the enthusiasm: the differences between Normal and AD are no more than a... 18 Sep 2007. 

Van Leuven F. on PAPER: Ring S. et al., 2007, I stand in awe of this painstaking, comprehensive study from Ulrike Müller and coworkers. This... 21 Aug 2007. 

Van Leuven F. on PAPER: Jellinger KA. et al., 2007, I proposed (ICAD-2006, Madrid) that intracerebral bleedings observed in some amyloid mouse... 13 Aug 2007. 

Van Leuven F. on PAPER: Rockenstein E. et al., 2007, My initial enthusiasm, shared with commentator Tom Fagan, for this study was cooled when I tried... 21 Mar 2007. 

Van Leuven F. on NEWS: How Now, Phospho-tau? Sparing Synapses, Messing with Microtubules, While this study helps us to understand some of the actions of tau, several questions come to... 6 Jun 2006. 

Van Leuven F. on LIVE DISCUSSION: Gain or Loss of Function—Time to Shake up Assumptions on γ-Secretase in Alzheimer Disease?, One could fill many more pages with discussions on this topic, pro and con the different theses.... 1 Jun 2006. 

Van Leuven F. on NEWS: Early Events in AD Mice as Targets for Therapy, The first sentence of Pat McCaffrey's news summary is both enlightening and puzzling: "Alzheimer... 27 Mar 2006. 

Dewachter I, Terwel D, Van Leuven F. on NEWS: Is Motor Neuron Axonopathy behind Movement Problems in Alzheimer Disease?, The paper by Oliver Wirths in the group of Thomas Bayer is another instance connecting amyloid... 18 Mar 2006. 

Van Leuven F. on PAPER: Kojro E. et al., 2006, Activation of α-secretase activity to increase non-amyloidogenic processing of APP is definitely... 23 Jan 2006. 

Van Leuven F. on NEWS: SfN: Return of the Other—Tau Is Back, Part 4, One should not forget my favorite natural anti-oxidant, currently being tested in a limited... 19 Dec 2005. 

Dewachter I, Van Leuven F. on LIVE DISCUSSION: Messing with the Membrane—An Alternative Interpretation of the Amyloid-β Hypothesis, The 12 Faces of Amyloid The problem of the amyloid peptides always reminds us of an... 7 Oct 2005. 

Dewachter I, Van Leuven F. on PAPER: Marchesi VT. et al., 2005, The 12 Faces of Amyloid The problem of the amyloid peptides always reminds us of an... 7 Oct 2005. 

Van Leuven F. on NEWS: Amyloid Hypothesis—Closing the Spigot Helps, Temporarily, It is very satisfying to see a totally independent confirmation of our work, especially when... 28 Jul 2005. 

Van Leuven F. on NEWS: The Theology of Aβ: Presenilins Giveth, and They Taketh Away, The results reported by Raphaelle Pardossi-Piquard and colleagues are most interesting and also... 31 May 2005. 

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